Prof. Ciro Indolfi: Curriculum Vitae

Prof. Ciro Indolfi

Curriculum Vitae breve del Prof. Ciro Indolfi

Ciro Indolfi è Professore Ordinario di Cardiologia, Direttore dell’URT del CNR dell’Università Magna Graecia di Catanzaro, Direttore dell’Unità Operativa complessa di Cardiologia – Emodinamica – UTIC, Direttore del Centro di Ricerche delle Malattie Cardiovascolari dell’Università Magna Graecia.

È stato insignito dal Presidente della Repubblica del titolo di Ufficiale della Repubblica al merito scientifico. È Consulente del Ministero della Salute per la valutazione dei dispositivi medici. E’ stato Presidente della Società Italiana di Cardiologia Invasiva (GISE) ed è attualmente Presidente della Società Italiana di Cardiologia (SIC).

È stato Presidente del Comitato Etico del Policlinico Universitario Mater Domini. E’ stato membro della commissione del Minimal Data Setting della Società Europea di Cardiologia (ESC), membro della commissione della Società Europea di Cardiologia (ESC) per le linee guida sulle valvulopatie. Revisore delle linee guida dell’angioplastica Coronarica della Società Europea di Cardiologia.

Il Prof. Indolfi è stato allievo del Dr.John Ross Jr. presso la Division of Cardiology, University of California, San Diego, La Jolla, U.S.A., e del Prof. Massimo Chiariello, Università Federico II di Napoli.

È stato Direttore del Dipartimento di Scienze Mediche e Chirurgiche e della Scuola di Specializzazione in Cardiologia presso l’Università Magna Græcia di Catanzaro fino al 2013 e Coordinatore del Corso di Dottorato in Biotecnologie mediche.

Si è laureato in Medicina e Chirurgia nel 1979 presso l’Università di Napoli. Nello stesso anno ha conseguito l’abilitazione all’esercizio della professione presso l’Università degli Studi di Napoli. Nel 1982 si è specializzato in Malattie dell’Apparato Cardiovascolare presso l’Università di Firenze.

Nel 1985 si è specializzato in Medicina dello Sport presso l’Università Federico II di Napoli. Nel 1984 è stato visiting Scientist presso il Laboratorio di cateterismo cardiaco del NIH, Bethesda, MD, USA. È stato Presidente della Sezione Calabrese della Società Italiana di Cardiologia. Editor dell’edizione Italiana del Cath Sap dell’American College of Cardiology.

Ha conseguito i seguenti riconoscimenti: Research Awards: Società Italiana di Cardiologia; Squibb Award; SIC. Ha ricevuto un Research Grant dalla NATO ed un Educational Grant of the European Society of Cardiology. È stato direttore scientifico e fondatore del giornale Emodinamica.

È censito dalla VIA-Academy come un Top Italian Scientist (TIS) con un H-Index di 53. Negli ultimi anni il Prof. Indolfi si è particolarmente dedicato all’organizzazione di sistemi complessi in medicina, creando presso l’Università Magna Graecia laboratori avanzati di ricerca cardiovascolare di cardiologia molecolare, laboratori di fisiologia animale in vivo dotati di attrezzature avanzate di imaging cardiovascolare per lo studio di modelli geneticamente determinati.

È stato poi co-fondatore della Cardiologia Interventistica dell’Università Federico II ed ha organizzato ex-novo il laboratorio di Emodinamica della Clinica Mediterranea nel 1996.

Nel 2006 ha partecipato con il Prof. Venuta all’organizzazione del nuovo Policlinico presso il Campus di Germaneto, ritenuto dal punto di vista tecnologico e strutturale tra i più avanzati in Italia.

Nel 2000 ha creato ex-novo la Divisione di Cardiologia dell’Università Magna Graecia di Catanzaro diventata leader in Italia nel campo della cardiologia interventistica coronarica, delle valvole e delle aritmie cardiache.

Il Prof. Indolfi ha organizzato il primo centro pubblico in Calabria per il trattamento dell’infarto miocardico con l’angioplastica coronarica. Ha introdotto la TAVI nella Regione nel 2009, e dirige l’unico centro in Calabria che effettua la riparazione percutanea della valvola mitrale.

Linee di ricerca

L’attività di ricerca del Prof. Ciro Indolfi è testimoniata dalla pubblicazione di 239 manoscritti su prestigiose riviste internazionali, da seminari e presentazioni su invito a congressi di rilievo nazionale ed internazionale, nonché dall’acquisizione di finanziamenti per le attività di ricerca da enti pubblici e fondazioni private (Società Europea di Cardiologia ESC, NATO, PON, PRIN, AIRC, Ministero della Salute, Telethon, Regione Calabria). Il suo impact factor è superiore 1000, con relativo h-Index pari a 53. Il Prof. Indolfi svolge correntemente il ruolo di revisore per numerose riviste internazionali quali Circulation, JACC, Nature Medicine, Basic Research in Cardiology.

È titolare di tre brevetti nel campo della Cardiologia.

Relazione tra flusso coronarico e funzione del ventricolo sinistro durante ischemia. 

Questi studi, effettuati negli Stati Uniti, hanno stabilito l’importanza fondamentale del flusso subendocardico nel determinare il livello di funzione ventricolare sinistra durante ischemia. Tali studi hanno creato il framework concettuale per individuare i meccanismi fondamentali dell’ischemia miocardica e per l’utilizzo di strategie farmacologiche specifiche come i beta-bloccanti (Indolfi & Ross, Circulation 1989; Indolfi & Ross, Am J Physiol 1991).

Ruolo del sistema simpatico e dei recettori alfa-adrenergici coronarici. 

Sono stati studiati nell’uomo il ruolo del sistema nervoso simpatico e dei recettori alfa-adrenergici sul flusso coronarico. È stata dimostrata per la prima volta la presenza dei recettori alfa2 adrenergici che, se stimolati, provocano vasocostrizione (Indolfi et al, Circulation 1994; Indolfi et al, Circulation 1995). Inoltre ha dimostrato il ruolo della stimolazione del sistema simpatico dopo angioplastica coronarica.

Biologia Vascolare. 

Dal 1990 il Prof. Indolfi ha studiato i meccanismi fondamentali della ristenosi e della trombosi dello stent. Ha studiato il ruolo della proliferazione della cellule muscolari lisce nel processo della ristenosi dopo angioplastica/stenting in vitro ed in modelli animali in vivo. Il Prof. Indolfi ha organizzato un laboratorio per modelli animali standardizzato e riproducibile di vascular injury con catetere a palloncino specifico per l’arteria carotide comune. In Prof. Indolfi ha studiato la trasmissione del segnale intracellulare dalla membrana al nucleo delle cellule muscolari lisce ed in particolare il pathway delle proteine Ras e del segnale dipendente dal cAMP-PKA (Indolfi et al, Nature Medicine 1995; Indolfi et al, Nature Medicine 1996; Indolfi et al, Nature Medicine 1997). I risultati di questi ed altri studi hanno rappresentato il frame-work concettuale per l’introduzione degli stent che rilasciano farmaci allo scopo di ridurre la proliferazione delle cellule muscoli lisce dopo impianto di stent e prevenire la ristenosi clinica.

Gli ultimi studi pubblicati su riviste prestigiose (Circulation, Circulation Research, Nature Cardiology Review) hanno dimostrato il ruolo di alcuni micro RNAs nella formazione della stenosi vascolare e della trombosi. Infine nel 2017 il Prof. Indolfi è stato uno dei coautori dello studio Define-Flair pubblicato sul New England Journal of Medicine che ha dimostrato la validità della misurazione del gradiente diastolico trans-stenotico nel predire eventi cardiovascolari maggiori nell’uomo.

Elenco delle pubblicazioni

1: Eyileten C, Wicik Z, De Rosa S, Mirowska-Guzel D, Soplinska A, Indolfi C, Jastrzebska-Kurkowska I, Czlonkowska A, Postula M. MicroRNAs as Diagnostic and Prognostic Biomarkers in Ischemic Stroke-A Comprehensive Review and Bioinformatic Analysis. Cells. 2018 Dec 6;7(12). pii: E249. doi: 10.3390/cells7120249.

2: Gaudio LT, Veltri P, De Rosa S, Indolfi C, Fragomeni G. Model and Application  to Support the Coronary Artery Diseases (CAD): Development and Testing. Interdiscip Sci. 2018 Dec 7. doi: 10.1007/s12539-018-0311-6.

3: Gori T, Polimeni A, Indolfi C, Räber L, Adriaenssens T, Münzel T. Predictors of stent thrombosis and their implications for clinical practice. Nat Rev Cardiol. 2018 Dec 5. doi: 10.1038/s41569-018-0118-5.

4: Polimeni A, Spaccarotella C, Mongiardo A, Indolfi C. Myocardial infarction after dog bite. Eur Heart J. 2018 Nov 28. doi: 10.1093/eurheartj/ehy782.

5: Gaudio LT, Caruso MV, De Rosa S, Indolfi C, Fragomeni G. Different Blood Flow Models in Coronary Artery Diseases: Effects on hemodynamic parameters. Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:3185-3188. doi: 10.1109/EMBC.2018.8512917.

6: Indolfi C, Iaconetti C, Gareri C, Polimeni A, De Rosa S. Non-coding RNAs in vascular remodeling and restenosis. Vascul Pharmacol. 2018 Oct 24. pii: S1537-1891(18)30105-8. doi: 10.1016/j.vph.2018.10.006.

7: Mazzitelli M, Torti C, Sabatino J, D’Ascoli GL, Costa C, Pisani V, Raffetti E, De Rosa S, Strazzulla A, Focà A, Liberto MC, Indolfi C; CARDIAC study group. Evaluation of cardiac function by global longitudinal strain before and after treatment with sofosbuvir-based regimens in HCV infected patients. BMC Infect Dis. 2018 Oct 16;18(1):518. doi: 10.1186/s12879-018-3426-9.

8: Indolfi C, Passafaro F, Sorrentino S, Spaccarotella C, Mongiardo A, Torella D, Polimeni A, Sabatino J, Curcio A, De Rosa S. Hand Laser Perfusion Imaging to Assess Radial Artery Patency: A Pilot Study. J Clin Med. 2018 Oct 2;7(10). pii:E319. doi: 10.3390/jcm7100319.

9: Torella D, Iaconetti C, Tarallo R, Marino F, Giurato G, Veneziano C, Aquila I, Scalise M, Mancuso T, Cianflone E, Valeriano C, Marotta P, Tammè L, Vicinanza C, Sasso FC, Cozzolino D, Torella M, Weisz A, Indolfi C. miRNA Regulation of the  Hyperproliferative Phenotype of Vascular Smooth Muscle Cells in Diabetes. Diabetes. 2018 Dec;67(12):2554-2568. doi: 10.2337/db17-1434.

10: Yasuda M, Iwanaga Y, Kawamura T, Nakamura T, De Rosa S, Indolfi C, Miyazaki S. Diagnostic value of cardiac magnetic resonance and fluorodeoxyglucose-positron emission tomography for cardiac sarcoidosis with previous myocardial infarction: A case report. Medicine (Baltimore). 2018 Aug;97(35):e11938. doi:10.1097/MD.0000000000011938. PubMed PMID: 30170386.

11: Escaned J, Ryan N, Mejía-Rentería H, Cook CM, Dehbi HM, Alegria-Barrero E, Alghamdi A, Al-Lamee R, Altman J, Ambrosia A, Baptista SB, Bertilsson M, Bhindi R, Birgander M, Bojara W, Brugaletta S, Buller C, Calais F, Silva PC, Carlsson J, Christiansen EH, Danielewicz M, Di Mario C, Doh JH, Erglis A, Erlinge D, Gerber RT, Going O, Gudmundsdottir I, Härle T, Hauer D, Hellig F, Indolfi C, Jakobsen L, Janssens L, Jensen J, Jeremias A, Kåregren A, Karlsson AC, Kharbanda RK, Khashaba A, Kikuta Y, Krackhardt F, Koo BK, Koul S, Laine M, Lehman SJ, Lindroos P, Malik IS, Maeng M, Matsuo H, Meuwissen M, Nam CW, Niccoli G, Nijjer SS, Olsson H, Olsson SE, Omerovic E, Panayi G, Petraco R, Piek JJ, Ribichini F, Samady H, Samuels B, Sandhall L, Sapontis J, Sen S, Seto AH, Sezer M, Sharp ASP, Shin ES, Singh J, Takashima H, Talwar S, Tanaka N, Tang K, Van Belle E, van Royen N, Varenhorst C, Vinhas H, Vrints CJ, Walters D, Yokoi H, Fröbert O, Patel MR, Serruys P, Davies JE, Götberg M. Safety of the Deferral of Coronary Revascularization on the Basis of Instantaneous Wave-Free Ratio and Fractional Flow Reserve Measurements in Stable Coronary Artery Disease and Acute Coronary Syndromes. JACC Cardiovasc Interv. 2018 Aug 13;11(15):1437-1449. doi:10.1016/j.jcin.2018.05.029.

12: Tarantini G, Esposito G, Musumeci G, Fraccaro C, Franzone A, Castiglioni B, La Manna A, Limbruno U, Marchese A, Mauro C, Rigattieri S, Tarantino F, Gandolfo C, Santoro G, Violini R, Airoldi F, Albiero R, Balbi M, Baralis G, Bartorelli AL, Bedogni F, Benassi A, Berni A, Bonzani G, Bortone AS, Braito G, Briguori C, Brscic E, Calabrò P, Calchera I, Cappelli Bigazzi M, Caprioglio F, Castriota F, Cernetti C, Cicala C, Cioffi P, Colombo A, Colombo V, Contegiacomo G, Cremonesi A, D’Amico M, De Benedictis M, De Leo A, Di Biasi M, Di Girolamo D, Di Lorenzo E, Di Mario C, Dominici M, Ettori F, Ferrario M, Fioranelli M, Fischetti D, Gabrielli G, Giordano A, Giudice P, Greco C, Indolfi C, Leonzi O, Lettieri C, Loi B, Maddestra N, Marchionni N, Marrozzini C, Medda M, Missiroli B, My L, Oreglia JA, Palmieri C, Pantaleo P, Paparoni SR, Parodi G, Petronio AS, Piatti L, Piccaluga E, Pierli C, Perkan A, Pitì A, Poli A, Ramondo AB, Reale MA, Reimers B, Ribichini FL, Rosso R, Saccà S, Sacra C, Santarelli A, Sardella G, Satullo G, Scalise F, Siviglia M, Spedicato L, Stabile A, Tamburino C, Tesorio TNM, Tolaro S, Tomai F, Trani C, Valenti R, Valsecchi O, Valva G, Varbella F, Vigna C, Vignali L, Berti S. [Updated SICI-GISE position paper on institutional and operator requirements for transcatheter aortic valve implantation]. G Ital Cardiol (Rome). 2018 Sep;19(9):519-529. doi: 10.1714/2951.29672.

13: Polimeni A, Anadol R, Münzel T, De Rosa S, Indolfi C, Gori T. Predictors of bioresorbable scaffold failure in STEMI patients at 3 years follow-up. Int J Cardiol. 2018 Oct 1;268:68-74. doi: 10.1016/j.ijcard.2018.04.081.

14: Aquila I, Petullà M, Torella D, Indolfi C. Re-broken and remended male heart. Eur Heart J. 2018 Jul 11. doi: 10.1093/eurheartj/ehy401.

15: Scumaci D, Oliva A, Concolino A, Curcio A, Fiumara CV, Tammè L, Campuzano O, Pascali VL, Coll M, Iglesias A, Berne P, Casu G, Olivo E, Ausania F, Ricci P, Indolfi C, Brugada J, Brugada R, Cuda G. Integration of “Omics” Strategies for Biomarkers Discovery and for the Elucidation of Molecular Mechanisms Underlying Brugada Syndrome. Proteomics Clin Appl. 2018 Nov;12(6):e1800065. doi:10.1002/prca.201800065.

16: Torella M, Aquila I, Chiodini P, Amarelli C, Romano G, Della Ratta EE, De Feo M, Della Corte A, Indolfi C, Torella D, De Santo LS. Low-dose anticoagulation after isolated mechanical aortic valve replacement with Liva Nova Bicarbon prosthesis: A post hoc analysis of LOWERING-IT Trial. Sci Rep. 2018 May 30;8(1):8405. doi: 10.1038/s41598-018-26528-9.

17: Santarpia G, Passafaro F, Pasceri E, Mongiardo A, Curcio A, Indolfi C. Inadvertent defibrillator lead placement into the left ventricle after MitraClip implantation: A case report. Medicine (Baltimore). 2018 May;97(19):e0733. doi:10.1097/MD.0000000000010733

18: Kikuta Y, Cook CM, Sharp ASP, Salinas P, Kawase Y, Shiono Y, Giavarini A, Nakayama M, De Rosa S, Sen S, Nijjer SS, Al-Lamee R, Petraco R, Malik IS, Mikhail GW, Kaprielian RR, Wijntjens GWM, Mori S, Hagikura A, Mates M, Mizuno A, Hellig F, Lee K, Janssens L, Horie K, Mohdnazri S, Herrera R, Krackhardt F, Yamawaki M, Davies J, Takebayashi H, Keeble T, Haruta S, Ribichini F, Indolfi C, Mayet J, Francis DP, Piek JJ, Di Mario C, Escaned J, Matsuo H, Davies JE. Pre-Angioplasty Instantaneous Wave-Free Ratio Pullback Predicts Hemodynamic Outcome In Humans With Coronary Artery Disease: Primary Results of the International Multicenter iFR GRADIENT Registry. JACC Cardiovasc Interv. 2018 Apr 23;11(8):757-767. doi:10.1016/j.jcin.2018.03.005. PubMed PMID: 29673507.

19: Pordzik J, Pisarz K, De Rosa S, Jones AD, Eyileten C, Indolfi C, Malek L, Postula M. The Potential Role of Platelet-Related microRNAs in the Development of Cardiovascular Events in High-Risk Populations, Including Diabetic Patients: A Review. Front Endocrinol (Lausanne). 2018 Mar 20;9:74. doi: 10.3389/fendo.2018.00074. eCollection 2018.

20: Indolfi C, Spaccarotella C, Yasuda M, De Rosa S. Climbing the hill of left main coronary artery revascularization: percutaneous coronary intervention or coronary artery bypass graft? J Thorac Dis. 2018 Feb;10(2):576-580. doi:10.21037/jtd.2017.12.116.

21: Indolfi C, Bartorelli AL, Berti S, Golino P, Esposito G, Musumeci G, Petronio S, Tamburino C, Tarantini G, Ussia G, Vassanelli C, Spaccarotella C, Violini R, Mercuro G, Romeo F. Updated clinical indications for transcatheter aortic valve implantation in patients with severe aortic stenosis: expert opinion of the Italian Society of Cardiology and GISE. J Cardiovasc Med (Hagerstown). 2018 May;19(5):197-210. doi: 10.2459/JCM.0000000000000636

22: Vicinanza C, Aquila I, Cianflone E, Scalise M, Marino F, Mancuso T, Fumagalli F, Giovannone ED, Cristiano F, Iaccino E, Marotta P, Torella A, Latini R, Agosti  V, Veltri P, Urbanek K, Isidori AM, Saur D, Indolfi C, Nadal-Ginard B, Torella D. Kit(cre) knock-in mice fail to fate-map cardiac stem cells. Nature. 2018 Mar 21;555(7697):E1-E5. doi: 10.1038/nature25771.

23: Irace C, De Rosa S, Tripolino C, Ambrosio G, Covello C, Abramo E, Carallo C,  Mongiardo A, Spaccarotella C, Torella D, Gnasso A, Indolfi C. Delayed flow-mediated vasodilation and critical coronary stenosis. J Investig Med. 2018 Jun;66(5):1-7. doi: 10.1136/jim-2017-000644.

24: Chiefari E, De Rosa S, Arcidiacono B, Foti D, Indolfi C, Brunetti A. Comment on Li et al. HMGA1: A novel predisposing gene for acute myocardial infarction. Int J Cardiol. 2018 Apr 1;256:38. doi: 10.1016/j.ijcard.2018.01.109.

25: Yasuda M, Spaccarotella C, Mongiardo A, De Rosa S, Torella D, Indolfi C. Migration of a stent from left main and its retrieval from femoral artery: A case report. Medicine (Baltimore). 2017 Dec;96(50):e9281. doi: 10.1097/MD.0000000000009281.

26: De Rosa S, Arcidiacono B, Chiefari E, Brunetti A, Indolfi C, Foti DP. Type 2 Diabetes Mellitus and Cardiovascular Disease: Genetic and Epigenetic Links. Front Endocrinol (Lausanne). 2018 Jan 17;9:2. doi: 10.3389/fendo.2018.00002. eCollection 2018.

27: Labate A, Mumoli L, Curcio A, Tripepi G, D’Arrigo G, Ferlazzo E, Aguglia U, Indolfi C, Quattrone A, Gambardella A. Value of clinical features to differentiate refractory epilepsy from mimics: a prospective longitudinal cohort study. Eur J Neurol. 2018 May;25(5):711-717. doi: 10.1111/ene.13579.

28: Marotta P, Cianflone E, Aquila I, Vicinanza C, Scalise M, Marino F, Mancuso T, Torella M, Indolfi C, Torella D. Combining cell and gene therapy to advance cardiac regeneration. Expert Opin Biol Ther. 2018 Apr;18(4):409-423. doi: 10.1080/14712598.2018.1430762.

29: Indolfi C, Spaccarotella C, Yasuda M, De Rosa S. The outlook of prognostic indicators for the Takotsubo syndrome. Int J Cardiol. 2018 Mar 15;255:158-159. doi: 10.1016/j.ijcard.2018.01.012.

30: Sorrentino S, Iaconetti C, De Rosa S, Polimeni A, Sabatino J, Gareri C, Passafaro F, Mancuso T, Tammè L, Mignogna C, Camastra C, Esposito G, Curcio A, Torella D, Indolfi C. Hindlimb Ischemia Impairs Endothelial Recovery and Increases Neointimal Proliferation in the Carotid Artery. Sci Rep. 2018 Jan 15;8(1):761. doi: 10.1038/s41598-017-19136-6.

31: De Rosa S, Polimeni A, Petraco R, Davies JE, Indolfi C. Diagnostic Performance of the Instantaneous Wave-Free Ratio: Comparison With Fractional Flow Reserve. Circ Cardiovasc Interv. 2018 Jan;11(1):e004613. doi: 10.1161/CIRCINTERVENTIONS.116.004613.

32: De Rosa S, Eposito F, Carella C, Strangio A, Ammirati G, Sabatino J, Abbate FG, Iaconetti C, Liguori V, Pergola V, Polimeni A, Coletta S, Gareri C, Trimarco B, Stabile G, Curcio A, Indolfi C, Rapacciuolo A. Transcoronary concentration gradients of circulating microRNAs in heart failure. Eur J Heart Fail. 2018 Jun;20(6):1000-1010. doi: 10.1002/ejhf.1119.

33: Santarpia G, De Rosa S, Sabatino J, Curcio A, Indolfi C. Should We Maintain Anticoagulation after Successful Radiofrequency Catheter Ablation of Atrial Fibrillation? The Need for a Randomized Study. Front Cardiovasc Med. 2017 Dec 21;4:85. doi: 10.3389/fcvm.2017.00085. eCollection 2017.

34: De Rosa S, Sievert H, Sabatino J, Polimeni A, Sorrentino S, Indolfi C. Percutaneous Closure Versus Medical Treatment in Stroke Patients With Patent Foramen Ovale: A Systematic Review and Meta-analysis. Ann Intern Med. 2018 Mar 6;168(5):343-350. doi: 10.7326/M17-3033.

35: Sorrentino S, Giustino G, Moalem K, Indolfi C, Mehran R, Dangas GD. Antithrombotic Treatment after Transcatheter Heart Valves Implant. Semin Thromb Hemost. 2018 Feb;44(1):38-45. doi: 10.1055/s-0037-1607457.

36: Indolfi C, Sabatino J, De Rosa S, Mongiardo A, Ricci P, Spaccarotella C. Description and Validation of TAVIApp: A Novel Mobile Application for Support of Physicians in the Management of Aortic Stenosis-Management of Aortic Stenosis with TAVIApp. Biomed Res Int. 2017;2017:9027597. doi: 10.1155/2017/9027597.

37: D’Onofrio A, La Rovere MT, Emdin M, Capucci A, Sinagra G, Bianchi V, Pisanò ECL, Pieragnoli P, Tespili M, Luzi M, Talarico A, Zecchin M, Rapacciuolo A, Piacenti M, Indolfi C, Arias MA, Diemberger I, Checchinato C, Boriani G, Padeletti L. Implantable cardioverter-defibrillator-computed respiratory disturbance index accurately identifies severe sleep apnea: The DASAP-HF study. Heart Rhythm. 2018 Feb;15(2):211-217. doi: 10.1016/j.hrthm.2017.09.038.

38: Polimeni A, Weissner M, Schochlow K, Ullrich H, Indolfi C, Dijkstra J, Anadol R, Münzel T, Gori T. Incidence, Clinical Presentation, and Predictors of Clinical Restenosis in Coronary Bioresorbable Scaffolds. JACC Cardiovasc Interv. 2017 Sep  25;10(18):1819-1827. doi: 10.1016/j.jcin.2017.07.034

39: Curcio A, De Rosa S, Indolfi C. Should we rethink the indications for implantable cardioverter-defibrillators in non-ischaemic dilated cardiomyopathy? Eur J Heart Fail. 2018 Mar;20(3):417-419. doi: 10.1002/ejhf.948.

40: De Rosa S, Polimeni A, Sabatino J, Indolfi C. Long-term outcomes of coronary artery bypass grafting versus stent-PCI for unprotected left main disease: a meta-analysis. BMC Cardiovasc Disord. 2017 Sep 6;17(1):240. doi:10.1186/s12872-017-0664-5.

41: Vicinanza C, Aquila I, Scalise M, Cristiano F, Marino F, Cianflone E, Mancuso T, Marotta P, Sacco W, Lewis FC, Couch L, Shone V, Gritti G, Torella A, Smith AJ, Terracciano CM, Britti D, Veltri P, Indolfi C, Nadal-Ginard B, Ellison-Hughes GM, Torella D. Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification. Cell Death Differ. 2017 Dec;24(12):2101-2116. doi: 10.1038/cdd.2017.130.

42: Niccoli G, Indolfi C, Davies JE. Evaluation of intermediate coronary stenoses in acute coronary syndromes using pressure guidewire. Open Heart. 2017 Jun 14;4(2):e000431. doi: 10.1136/openhrt-2016-000431. eCollection 2017.

43: Pulignano G, Gulizia MM, Baldasseroni S, Bedogni F, Cioffi G, Indolfi C, Romeo F, Murrone A, Musumeci F, Parolari A, Patanè L, Pino PG, Mongiardo A, Spaccarotella C, Di Bartolomeo R, Musumeci G. ANMCO/SIC/SICI-GISE/SICCH Executive Summary of Consensus Document on Risk Stratification in elderly patients with aortic stenosis before surgery or transcatheter aortic valve replacement. Eur Heart J Suppl. 2017 May;19(Suppl D):D354-D369. doi: 10.1093/eurheartj/sux012.

44: Aquila I, Marino F, Cianflone E, Marotta P, Torella M, Mollace V, Indolfi C, Nadal-Ginard B, Torella D. The use and abuse of Cre/Lox recombination to identify adult cardiomyocyte renewal rate and origin. Pharmacol Res. 2018 Jan;127:116-128. doi: 10.1016/j.phrs.2017.06.012

45: Polimeni A, Anadol R, Münzel T, Indolfi C, De Rosa S, Gori T. Long-term outcome of bioresorbable vascular scaffolds for the treatment of coronary artery disease: a meta-analysis of RCTs. BMC Cardiovasc Disord. 2017 Jun 7;17(1):147. doi: 10.1186/s12872-017-0586-2.

46: Testa L, De Carlo M, Petrolini A, Rapetto C, Varbella F, Cortese B, Gabrielli G, Geraci S, Loi B, Boccuzzi G, Tarantini G, Fischetti D, Calabria P, Tomai F, Ribichini F, Tamburino C, Indolfi C, Bartorelli AL, Petronio AS, Bedogni F. One-year clinical results of the Italian diffuse/multivessel disease ABSORB prospective registry (IT-DISAPPEARS). EuroIntervention. 2017 Jul 20;13(4):424-431. doi: 10.4244/EIJ-D-17-00246.

47: Gareri C, Iaconetti C, Sorrentino S, Covello C, De Rosa S, Indolfi C. miR-125a-5p Modulates Phenotypic Switch of Vascular Smooth Muscle Cells by Targeting ETS-1. J Mol Biol. 2017 Jun 16;429(12):1817-1828. doi: 10.1016/j.jmb.2017.05.008.

48: Spaccarotella C, Mongiardo A, De Rosa S, Indolfi C. Transcatheter aortic valve implantation in patients at intermediate surgical risk. Int J Cardiol. 2017 Sep 15;243:161-168. doi: 10.1016/j.ijcard.2017.04.107.

49: Sorrentino S, Giustino G, Mehran R, Kini AS, Sharma SK, Faggioni M, Farhan S, Vogel B, Indolfi C, Dangas GD. Everolimus-Eluting Bioresorbable Scaffolds Versus Everolimus-Eluting Metallic Stents. J Am Coll Cardiol. 2017 Jun 27;69(25):3055-3066. doi: 10.1016/j.jacc.2017.04.011.

50: Davies JE, Sen S, Dehbi HM, Al-Lamee R, Petraco R, Nijjer SS, Bhindi R, Lehman SJ, Walters D, Sapontis J, Janssens L, Vrints CJ, Khashaba A, Laine M, Van Belle E, Krackhardt F, Bojara W, Going O, Härle T, Indolfi C, Niccoli G, Ribichini F, Tanaka N, Yokoi H, Takashima H, Kikuta Y, Erglis A, Vinhas H, Canas  Silva P, Baptista SB, Alghamdi A, Hellig F, Koo BK, Nam CW, Shin ES, Doh JH, Brugaletta S, Alegria-Barrero E, Meuwissen M, Piek JJ, van Royen N, Sezer M, Di Mario C, Gerber RT, Malik IS, Sharp ASP, Talwar S, Tang K, Samady H, Altman J, Seto AH, Singh J, Jeremias A, Matsuo H, Kharbanda RK, Patel MR, Serruys P, Escaned J. Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI. N Engl J Med. 2017 May 11;376(19):1824-1834. doi: 10.1056/NEJMoa1700445.

51: Curcio A, Santarpia G, Indolfi C. The Brugada Syndrome – From Gene to Therapy. Circ J. 2017 Feb 24;81(3):290-297. doi: 10.1253/circj.CJ-16-0971.

52: Zeng Y, Cavalcante R, Tenekecioglu E, Suwannasom P, Sotomi Y, Collet C, Abdelghani M, Jonker H, Digne F, Horstkotte D, Zehender M, Indolfi C, Saia F, Fiorilli R, Chevalier B, Bolognese L, Goicolea J, Nie S, Onuma Y, Serruys PW; investigators of Absorb II study. Comparative assessment of “plaque/media” change on three modalities of IVUS immediately after implantation of either everolimus-eluting bioresorbable vascular scaffold or everolimus-eluting metallic stent in Absorb II study. Int J Cardiovasc Imaging. 2017 Apr;33(4):441-449. doi: 10.1007/s10554-016-1033-7.

53: Aquila I, Fernández-Golfín C, Rincon LM, González A, García Martín A, Hinojar R, Jimenez Nacher JJ, Indolfi C, Zamorano JL. Fully automated software for mitral annulus evaluation in chronic mitral regurgitation by 3-dimensional transesophageal echocardiography. Medicine (Baltimore). 2016 Dec;95(49):e5387.

54: Giordano A, Corcione N, Biondi-Zoccai G, Berti S, Petronio AS, Pierli C, Presbitero P, Giudice P, Sardella G, Bartorelli AL, Bonmassari R, Indolfi C, Marchese A, Brscic E, Cremonesi A, Testa L, Brambilla N, Bedogni F. Patterns and trends of transcatheter aortic valve implantation in Italy: insights from RISPEVA. J Cardiovasc Med (Hagerstown). 2017 Feb;18(2):96-102. doi: 10.2459/JCM.0000000000000489.

55: Pulignano G, Gulizia MM, Baldasseroni S, Bedogni F, Cioffi G, Indolfi C, Romeo F, Murrone A, Musumeci F, Parolari A, Patanè L, Pino PG, Mongiardo A, Spaccarotella C, Di Bartolomeo R, Musumeci G. [ANMCO/SIC/SICI-GISE/SICCH Consensus document: Risk stratification in elderly patients undergoing cardiac surgery and transcatheter aortic valve implantation]. G Ital Cardiol (Rome). 2016 Sep;17(9):756-789. doi: 10.1714/2448.25664.

56: De Rosa S, Chiefari E, Salerno N, Ventura V, D’Ascoli GL, Arcidiacono B, Ambrosio G, Bilotta FL, Torella D, Foti D, Indolfi C, Brunetti A. HMGA1 is a novel candidate gene for myocardial infarction susceptibility. Int J Cardiol. 2017 Jan 15;227:331-334. doi: 10.1016/j.ijcard.2016.11.088.

57: Indolfi C, De Rosa S, Colombo A. Bioresorbable vascular scaffolds – basic concepts and clinical outcome. Nat Rev Cardiol. 2016 Dec;13(12):719-729. doi:10.1038/nrcardio.2016.151.

58: Kennedy MW, Fabris E, Ijsselmuiden AJ, Nef H, Reith S, Escaned J, Alfonso F, van Royen N, Wojakowski W, Witkowski A, Indolfi C, Ottervanger JP, Suryapranata H, Kedhi E. Combined optical coherence tomography morphologic and fractional flow reserve hemodynamic assessment of non- culprit lesions to better predict adverse event outcomes in diabetes mellitus patients: COMBINE (OCT-FFR) prospective study. Rationale and design. Cardiovasc Diabetol. 2016 Oct 10;15(1):144.

59: Barillà F, Pelliccia F, Borzi M, Camici P, Cas LD, Di Biase M, Indolfi C, Mercuro G, Montemurro V, Padeletti L, Filardi PP, Vizza CD, Romeo F; 2015–2016 Board of the Italian Society of Cardiology. Optimal duration of dual anti-platelet therapy after percutaneous coronary intervention: 2016 consensus position of the Italian Society of Cardiology. J Cardiovasc Med (Hagerstown). 2017 Jan;18(1):1-9.

60: Caiazzo G, Longo G, Giavarini A, Kilic ID, Fabris E, Serdoz R, Mattesini A, Foin N, Secco GG, De Rosa S, Indolfi C, Di Mario C. Optical coherence tomography guidance for percutaneous coronary intervention with bioresorbable scaffolds. Int J Cardiol. 2016 Oct 15;221:352-8. doi: 10.1016/j.ijcard.2016.07.033.

61: Carino A, De Rosa S, Sorrentino S, Polimeni A, Sabatino J, Caiazzo G, Torella D, Spaccarotella C, Mongiardo A, Strangio A, Filippis C, Indolfi C. Modulation of Circulating MicroRNAs Levels during the Switch from Clopidogrel to Ticagrelor. Biomed Res Int. 2016;2016:3968206. doi: 10.1155/2016/3968206.

62: Gargiulo G, Sannino A, Capodanno D, Barbanti M, Buccheri S, Perrino C, Capranzano P, Indolfi C, Trimarco B, Tamburino C, Esposito G. Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement: A Systematic  Review and Meta-analysis. Ann Intern Med. 2016 Sep 6;165(5):334-44. doi:10.7326/M16-0060.

63: Curcio A, Mazzanti A, Bloise R, Monteforte N, Indolfi C, Priori SG, Napolitano C. Clinical Presentation and Outcome of Brugada Syndrome Diagnosed With the New 2013 Criteria. J Cardiovasc Electrophysiol. 2016 Aug;27(8):937-43. doi: 10.1111/jce.12997.

64: Curcio A, DE Rosa S, Sabatino J, DE Luca S, Bochicchio A, Polimeni A, Santarpia G, Ricci P, Indolfi C. Clinical Usefulness of a Mobile Application for the Appropriate Selection of the Antiarrhythmic Device in Heart Failure. Pacing Clin Electrophysiol. 2016 Jul;39(7):696-702. doi: 10.1111/pace.12872.

65: Gareri C, De Rosa S, Indolfi C. MicroRNAs for Restenosis and Thrombosis After Vascular Injury. Circ Res. 2016 Apr 1;118(7):1170-84. doi: 10.1161/CIRCRESAHA.115.308237.

66: Curcio A, Cascini GL, De Rosa S, Pasceri E, Veneziano C, Cipullo S, Saccomanno M, Santarpia G, Cuda G, Indolfi C. (123)I-mIBG imaging predicts functional improvement and clinical outcome in patients with heart failure and CRT implantation. Int J Cardiol. 2016 Mar 15;207:107-9. doi:10.1016/j.ijcard.2016.01.131.

67: Caruso MV, De Rosa S, Indolfi C, Fragomeni G. Computational analysis of stenosis geometry effects on right coronary hemodynamics. Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:981-4. doi: 10.1109/EMBC.2015.7318528.

68: Polimeni A, Passafaro F, De Rosa S, Sorrentino S, Torella D, Spaccarotella C, Mongiardo A, Indolfi C. Clinical and Procedural Outcomes of 5-French versus 6-French Sheaths in Transradial Coronary Interventions. Medicine (Baltimore).2015 Dec;94(52):e2170. doi: 10.1097/MD.0000000000002170.

69: Iaconetti C, Sorrentino S, De Rosa S, Indolfi C. Exosomal miRNAs in Heart Disease. Physiology (Bethesda). 2016 Jan;31(1):16-24. doi:10.1152/physiol.00029.2015.

70: Sorrentino S, De Rosa S, Ambrosio G, Mongiardo A, Spaccarotella C, Polimeni A, Sabatino J, Torella D, Caiazzo G, Indolfi C. The duration of balloon inflation affects the luminal diameter of coronary segments after bioresorbable vascular scaffolds deployment. BMC Cardiovasc Disord. 2015 Dec 11;15:169. doi: 10.1186/s12872-015-0163-5.

71: Polimeni A, De Rosa S, Sabatino J, Sorrentino S, Indolfi C. Impact of intracoronary adenosine administration during primary PCI: A meta-analysis. Int J Cardiol. 2016 Jan 15;203:1032-41. doi: 10.1016/j.ijcard.2015.11.086.

72: De Rosa S, Indolfi C. Circulating microRNAs as Biomarkers in Cardiovascular Diseases. Exp Suppl. 2015;106:139-149. doi: 10.1007/978-3-0348-0955-9_6.

73: Serra R, de Franciscis S, Grande R, Butrico L, Perri P, Indolfi C, Mastroroberto P. Endovascular repair for acute traumatic transection of the descending thoracic aorta: experience of a single centre with a 12-years follow up. J Cardiothorac Surg. 2015 Nov 21;10:171. doi: 10.1186/s13019-015-0388-5

74: Gargiulo G, Capodanno D, Sannino A, Barbanti M, Perrino C, Capranzano P, Stabile E, Indolfi C, Trimarco B, Tamburino C, Esposito G. New-onset atrial fibrillation and increased mortality after transcatheter aortic valve implantation: A causal or spurious association? Int J Cardiol. 2016 Jan 15;203:264-6. doi: 10.1016/j.ijcard.2015.10.133.

75: Caiazzo G, Kilic ID, Fabris E, Serdoz R, Mattesini A, Foin N, De Rosa S, Indolfi C, Di Mario C. Absorb bioresorbable vascular scaffold: What have we learned after 5 years of clinical experience? Int J Cardiol. 2015 Dec 15;201:129-36. doi: 10.1016/j.ijcard.2015.07.101.

76: Caiazzo G, Kilic ID, Foin N, Fabris E, Serdoz R, Indolfi C, Di Mario C. Three-dimensional optical coherence tomography reconstruction of a long coronary artery dissection: advantages over intravascular ultrasound imaging. J Cardiovasc Med (Hagerstown). 2016 Dec;17 Suppl 2:e107-e108. doi:10.2459/JCM.0000000000000291.

77: Torella D, Indolfi C, Nadal-Ginard B. Generation of new cardiomyocytes after injury: de novo formation from resident progenitors vs. replication of pre-existing cardiomyocytes. Ann Transl Med. 2015 May;3(Suppl 1):S8. doi:10.3978/j.issn.2305-5839.2015.02.17.

78: Iaconetti C, De Rosa S, Polimeni A, Sorrentino S, Gareri C, Carino A, Sabatino J, Colangelo M, Curcio A, Indolfi C. Down-regulation of miR-23b induces phenotypic switching of vascular smooth muscle cells in vitro and in vivo. Cardiovasc Res. 2015 Sep 1;107(4):522-33. doi: 10.1093/cvr/cvv141.

79: Santarpia G, Polimeni A, De Rosa S, Sabatino J, Curcio A, Indolfi C. First case of subcutaneous implantable cardioverter-defibrillator extrusion. Int J Cardiol. 2015 Aug 1;192:19-20. doi: 10.1016/j.ijcard.2015.04.280.

80: Santarpia G, De Rosa S, Polimeni A, Giampà S, Micieli M, Curcio A, Indolfi C. Efficacy and Safety of Non-Vitamin K Antagonist Oral Anticoagulants versus Vitamin K Antagonist Oral Anticoagulants in Patients Undergoing Radiofrequency Catheter Ablation of Atrial Fibrillation: A Meta-Analysis. PLoS One. 2015 May 14;10(5):e0126512. doi: 10.1371/journal.pone.0126512. eCollection 2015.

81: Vizza P, Curcio A, Tradigo G, Indolfi C, Veltri P. A framework for the atrial fibrillation prediction in electrophysiological studies. Comput Methods Programs Biomed. 2015 Jul;120(2):65-76. doi: 10.1016/j.cmpb.2015.04.001.

82: Mongiardo A, Spaccarotella C, Mascaro G, Pasceri E, Santarpia G, Indolfi C. Tips and tricks to implant a MitraClip in a patient with previous surgical closure of atrial septal defect. Int J Cardiol. 2015;187:264-6. doi: 10.1016/j.ijcard.2015.03.226.

83: Santarpia G, Curcio A, Sibilio G, Indolfi C. Clinical significance of non-vitamin K antagonist oral anticoagulants in the management of atrial fibrillation. Circ J. 2015;79(5):914-23. doi: 10.1253/circj.CJ-15-0319.

84: De Rosa S, Indolfi C. Letter by De Rosa and Indolfi regarding article, “Clinical presentation and outcomes of coronary in-stent restenosis across 3-stent generations”. Circ Cardiovasc Interv. 2015 Apr;8(4). pii: e002375. doi:10.1161/CIRCINTERVENTIONS.115.002375.

85: Bedogni F, Indolfi C, Ribichini F, Verna E, Leone AM, Polimeni A, Bollati M, Biondi-Zoccai G, Testa L, Berti S; Italian Society of Invasive Cardiology (SICI-GISE). [Position paper on the theoretical basis, practical application and health economic evaluation of the functional assessment of coronary lesions endorsed by the Italian Society of Invasive Cardiology (SICI-GISE)]. G Ital Cardiol (Rome). 2015 Feb;16(2):116-28. doi: 10.1714/1798.19590.

86: Indolfi C, Passafaro F, Mongiardo A, Spaccarotella C, Torella D, Sorrentino S, Polimeni A, Emanuele V, Curcio A, De Rosa S. Delayed sudden radial artery rupture after left transradial coronary catheterization: a case report. Medicine (Baltimore). 2015 Mar;94(10):e634. doi: 10.1097/MD.0000000000000634

87: Testa L, Biondi Zoccai G, Tomai F, Ribichini F, Indolfi C, Tamburino C, Bartorelli A, Petronio AS, Bedogni F, De Carlo M. Italian Diffuse/Multivessel Disease ABSORB Prospective Registry (IT-DISAPPEARS). Study design and rationale. J Cardiovasc Med (Hagerstown). 2015 Mar;16(3):253-8. doi: 10.2459/JCM.0000000000000219. PubMed PMID: 25469734.

88: Indolfi C, Mongiardo A, Spaccarotella C, Torella D, Caiazzo G, Polimeni A, Sorrentino S, Micieli M, Sabatino J, Curcio A, De Rosa S. The instantaneous wave-free ratio (iFR) for evaluation of non-culprit lesions in patients with acute coronary syndrome and multivessel disease. Int J Cardiol. 2015 Jan 15;178:46-54. doi: 10.1016/j.ijcard.2014.03.210.

89: Petraco R, Al-Lamee R, Gotberg M, Sharp A, Hellig F, Nijjer SS, Echavarria-Pinto M, van de Hoef TP, Sen S, Tanaka N, Van Belle E, Bojara W, Sakoda K, Mates M, Indolfi C, De Rosa S, Vrints CJ, Haine S, Yokoi H, Ribichini FL, Meuwissen M, Matsuo H, Janssens L, Katsumi U, Di Mario C, Escaned J, Piek J, Davies JE. Real-time use of instantaneous wave-free ratio: results of the ADVISE in-practice: an international, multicenter evaluation of instantaneous wave-free ratio in clinical practice. Am Heart J. 2014 Nov;168(5):739-48. doi:10.1016/j.ahj.2014.06.022.

90: Capranzano P, Testa L, Tamburino C, Capodanno D, Biondi-Zoccai G, Longo G,Tomai F, Ribichini F, Indolfi C, Bartorelli AL, Petronio AS, Bedogni F, La Manna A, Francaviglia B, De Carlo M, Tamburino C. [Technical features of Absorb(TM) BVS implantation in the IT-DISAPPEARS registry]. G Ital Cardiol (Rome). 2014Sep;15(9):475-81. doi: 10.1714/1640.17972.

91: Caiazzo G, De Rosa S, Torella D, Spaccarotella C, Mongiardo A, Giampà S, Micieli M, Palella E, Gulletta E, Indolfi C. Response to letter regarding, “administration of a loading dose has no additive effect on platelet aggregation  during the switch from ongoing clopidogrel treatment to ticagrelor in patients with acute coronary syndrome”. Circ Cardiovasc Interv. 2014 Aug;7(4):634. doi:10.1161/CIRCINTERVENTIONS.114.001716.

92: De Rosa S, Passafaro F, Polimeni A, Sorrentino S, Indolfi C. A novel quick and easy test for radial artery occlusion with the laser Doppler scan. JACC Cardiovasc Interv. 2014 Aug;7(8):e89-90. doi: 10.1016/j.jcin.2013.11.028.

93: Indolfi C, Mongiardo A, Spaccarotella C, Caiazzo G, Torella D, De Rosa S.Neointimal proliferation is associated with clinical restenosis 2 years after fully bioresorbable vascular scaffold implantation. Circ Cardiovasc Imaging. 2014 Jul;7(4):755-7. doi: 10.1161/CIRCIMAGING.114.001727.

94: Chieffo A, Buchanan GL, Parodi G, Versaci F, Bianchi RM, Valenti R, Saccà S, Mongiardo A, Span S, Migliorini A, Spaccarotella C, Reimers B, Antoniucci D, Indolfi C, Ferrari A, Maehara A, Mintz GS, Colombo A. Drug-eluting stent implantation in patients with acute coronary syndrome – the Activity of Platelets after Inhibition and Cardiovascular Events: Optical Coherence Tomography (APICE OCT) study. EuroIntervention. 2014 Dec;10(8):916-23. doi: 10.4244/EIJY14M06_10.

95: Campanile A, Sozzi FB, Consonni D, Piscione F, Sganzerla P, Indolfi C, Stabile A, Migliorini A, Antoniucci D, Ferraresi R, Boccuzzi G, Danzi GB. Primary PCI for the treatment of ectatic infarct-related coronary artery. Minerva Cardioangiol. 2014 Aug;62(4):327-33.

96: Indolfi C, Curcio A. Stargazing microRNA maps a new miR-21 star for cardiac hypertrophy. J Clin Invest. 2014 May;124(5):1896-8. doi: 10.1172/JCI75801.

97: Torella D, Ellison GM, Torella M, Vicinanza C, Aquila I, Iaconetti C, Scalise M, Marino F, Henning BJ, Lewis FC, Gareri C, Lascar N, Cuda G, Salvatore T, Nappi G, Indolfi C, Torella R, Cozzolino D, Sasso FC. Carbonic anhydrase activation is associated with worsened pathological remodeling in human ischemic diabetic cardiomyopathy. J Am Heart Assoc. 2014 Mar 26;3(2):e000434. doi:10.1161/JAHA.113.000434.

98: De Rosa S, Caiazzo G, Torella D, Indolfi C. Aspiration thrombectomy: an easily forgiven “latecomer”. J Am Coll Cardiol. 2014 May 20;63(19):2052-3. doi:10.1016/j.jacc.2013.12.038.

99: De Rosa S, Curcio A, Indolfi C. Emerging role of microRNAs in cardiovascular diseases. Circ J. 2014;78(3):567-75.

100: Caiazzo G, De Rosa S, Torella D, Spaccarotella C, Mongiardo A, Giampà S, Micieli M, Palella E, Gulletta E, Indolfi C. Administration of a loading dose has no additive effect on platelet aggregation during the switch from ongoing clopidogrel treatment to ticagrelor in patients with acute coronary syndrome. Circ Cardiovasc Interv. 2014 Feb;7(1):104-12. doi:10.1161/CIRCINTERVENTIONS.113.000512.

101: De Rosa S, Caiazzo G, Torella D, Indolfi C. Intracoronary versus intravenous abciximab bolus administration. J Am Coll Cardiol. 2014 Apr 8;63(13):1340-1341. doi: 10.1016/j.jacc.2013.08.1662.

102: De Rosa S, Torella D, Caiazzo G, Giampà S, Indolfi C. Left radial access for percutaneous coronary procedures: from neglected to performer? A meta-analysis of 14 studies including 7,603 procedures. Int J Cardiol. 2014 Jan 15;171(1):66-72. doi: 10.1016/j.ijcard.2013.11.046.

103: Iaconetti C, Gareri C, Polimeni A, Indolfi C. Non-coding RNAs: the “dark matter” of cardiovascular pathophysiology. Int J Mol Sci. 2013 Oct 9;14(10):19987-20018. doi: 10.3390/ijms141019987.

104: Indolfi C. [Who is the ideal patient for treatment with the Absorb™ bioresorbable vascular scaffold?]. G Ital Cardiol (Rome). 2013 Sep;14(9 Suppl 1):12S-14S. doi: 10.1714/1327.14695.

105: Ribichini F, Romano M, Rosiello R, La Vecchia L, Cabianca E, Caramanno G, Milazzo D, Loschiavo P, Rigattieri S, Musarò S, Pironi B, Fiscella A, Amico F, Indolfi C, Spaccarotella C, Bartorelli A, Trabattoni D, Della Rovere F, Rolandi A, Beqaraj F, Belli R, Sangiorgio P, Villani R, Berni A, Sheiban I, Lopera Quijada MJ, Cappi B, Ribaldi L, Vassanelli C; EXECUTIVE Trial Investigators. A clinical and angiographic study of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with multivessel coronary artery disease: the EXECUTIVE trial (EXecutive RCT: evaluating XIENCE V in a multi vessel disease). JACC Cardiovasc Interv. 2013 Oct;6(10):1012-22. doi: 10.1016/j.jcin.2013.05.016.

106: Ellison GM, Vicinanza C, Smith AJ, Aquila I, Leone A, Waring CD, Henning BJ, Stirparo GG, Papait R, Scarfò M, Agosti V, Viglietto G, Condorelli G, Indolfi C, Ottolenghi S, Torella D, Nadal-Ginard B. Adult c-kit(pos) cardiac stem cells are necessary and sufficient for functional cardiac regeneration and repair. Cell. 2013 Aug 15;154(4):827-42. doi: 10.1016/j.cell.2013.07.039.

107: Curcio A, Torella D, Iaconetti C, Pasceri E, Sabatino J, Sorrentino S, Giampà S, Micieli M, Polimeni A, Henning BJ, Leone A, Catalucci D, Ellison GM, Condorelli G, Indolfi C. MicroRNA-1 downregulation increases connexin 43 displacement and induces ventricular tachyarrhythmias in rodent hypertrophic hearts. PLoS One. 2013 Jul 26;8(7):e70158. doi: 10.1371/journal.pone.0070158.

108: De Rosa S, Caiazzo G, Torella D, Indolfi C. What accounts for the higher clinical efficacy of intracoronary abciximab? Int J Cardiol. 2013 Oct 9;168(4):4410. doi: 10.1016/j.ijcard.2013.05.033.

109: Perrino C, Schiattarella GG, Sannino A, Pironti G, Petretta MP, Cannavo A, Gargiulo G, Ilardi F, Magliulo F, Franzone A, Carotenuto G, Serino F, Altobelli GG, Cimini V, Cuocolo A, Lombardi A, Goglia F, Indolfi C, Trimarco B, Esposito G. Genetic deletion of uncoupling protein 3 exaggerates apoptotic cell death in the ischemic heart leading to heart failure. J Am Heart Assoc. 2013 May 20;2(3):e000086. doi: 10.1161/JAHA.113.000086.

110: Roccia F, Campolo B, Gallelli L, Spaccarotella C, Mongiardo A, Falcone D, Savino R, Pelaia G, Indolfi C, Maselli R. Effects of ambrisentan in a patient affected by combined pulmonary fibrosis and emphysema and by severe pulmonary hypertension: clinical, functional, and biomolecular findings. Clin Drug Investig. 2013 Jun;33(6):451-7. doi: 10.1007/s40261-013-0083-z.

111: Polimeni A, Curcio A, Indolfi C. Renal sympathetic denervation for treating resistant hypertension. Circ J. 2013;77(4):857-63.

112: Silvestre-Roig C, Fernández P, Esteban V, Pello ÓM, Indolfi C, Rodríguez C, Rodríguez-Calvo R, López-Maderuelo MD, Bauriedel G, Hutter R, Fuster V, Ibáñez B, Redondo JM, Martínez-González J, Andrés V. Inactivation of nuclear factor-Y inhibits vascular smooth muscle cell proliferation and neointima formation. Arterioscler Thromb Vasc Biol. 2013 May;33(5):1036-45. Doi: 10.1161/ATVBAHA.112.300580. Epub 2013 Feb 21. Erratum in: Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):e121. PubMed PMID: 23430616.

113: De Fazio P, Caroleo M, Rizza P, Cerminara G, De Serio D, Indolfi C, Segura-García C. Specific personality traits and coping styles predict affective symptoms in early post acute coronary syndrome inpatients. Int J Psychiatry Med. 2012;44(2):119-32.

114: Mastroroberto P, Ciranni S, Indolfi C. Extensive endovascular repair of thoracic aorta: observational analysis of the results and effects on spinal cord perfusion. J Cardiovasc Surg (Torino). 2013 Aug;54(4):523-30.

115: Polimeni A, De Rosa S, Indolfi C. Vascular miRNAs after balloon angioplasty. Trends Cardiovasc Med. 2013 Jan;23(1):9-14. doi: 10.1016/j.tcm.2012.08.004.

116: Di Domenico M, Scumaci D, Grasso S, Gaspari M, Curcio A, Oliva A, Ausania F, Di Nunzio C, Ricciardi C, Santini AC, Rizzo FA, Romano Carratelli C, Lamberti M,  Conti D, La Montagna R, Tomei V, Malafoglia V, Pascali VL, Ricci P, Indolfi C, Costanzo F, Cuda G. Biomarker discovery by plasma proteomics in familial Brugada Syndrome. Front Biosci (Landmark Ed). 2013 Jan 1;18:564-71.

117: De Rosa S, Caiazzo G, Torella D, Indolfi C. Intracoronary abciximab reduces death and major adverse cardiovascular events in acute coronary syndromes: a meta-analysis of clinical trials. Int J Cardiol. 2013 Sep 30;168(2):1298-305. doi: 10.1016/j.ijcard.2012.12.003. Epub 2012 Dec 27. PubMed PMID: 23273690.

118: Iaconetti C, Polimeni A, Sorrentino S, Sabatino J, Pironti G, Esposito G, Curcio A, Indolfi C. Inhibition of miR-92a increases endothelial proliferation and migration in vitro as well as reduces neointimal proliferation in vivo after vascular injury. Basic Res Cardiol. 2012 Sep;107(5):296. doi:10.1007/s00395-012-0296-y.

119: Giugliano G, Di Serafino L, Perrino C, Schiano V, Laurenzano E, Cassese S, De Laurentis M, Schiattarella GG, Brevetti L, Sannino A, Gargiulo G, Franzone A, Indolfi C, Piscione F, Trimarco B, Esposito G. Effects of successful percutaneous lower extremity revascularization on cardiovascular outcome in patients with peripheral arterial disease. Int J Cardiol. 2013 Sep 10;167(6):2566-71. doi:10.1016/j.ijcard.2012.06.055.

120: Cuda G, Lentini M, Gallo L, Lucia FG, Giacinto Carinci L, Mancuso S, Biondi RA, Sinopoli R, Casadonte R, Guzzi PH, Cannataro M, Mongiardo A, Iaconetti C, Bochicchio A, Curcio A, Torella D, Ricci P, Indolfi C, Costanzo F. High sensitive troponin T in individuals with chest pain of presumed ischemic origin. Front Biosci (Elite Ed). 2012 Jun 1;4:2322-7.

121: Torella D, Iaconetti C, Catalucci D, Ellison GM, Leone A, Waring CD, Bochicchio A, Vicinanza C, Aquila I, Curcio A, Condorelli G, Indolfi C. MicroRNA-133 controls vascular smooth muscle cell phenotypic switch in vitro and vascular remodeling in vivo. Circ Res. 2011 Sep 30;109(8):880-93. doi:10.1161/CIRCRESAHA.111.240150.

122: Ellison GM, Torella D, Dellegrottaglie S, Perez-Martinez C, Perez de Prado A, Vicinanza C, Purushothaman S, Galuppo V, Iaconetti C, Waring CD, Smith A, Torella M, Cuellas Ramon C, Gonzalo-Orden JM, Agosti V, Indolfi C, Galiñanes M, Fernandez-Vazquez F, Nadal-Ginard B. Endogenous cardiac stem cell activation by insulin-like growth factor-1/hepatocyte growth factor intracoronary injection fosters survival and regeneration of the infarcted pig heart. J Am Coll Cardiol. 2011 Aug 23;58(9):977-86. doi: 10.1016/j.jacc.2011.05.013.

123: Indolfi C. [ESC/EACTS guidelines on myocardial revascularization: the interventional cardiologist’s point of view]. G Ital Cardiol (Rome). 2011Apr;12(4):245-50.

124: Curcio A, Torella D, Indolfi C. Mechanisms of smooth muscle cell proliferation and endothelial regeneration after vascular injury and stenting: approach to therapy. Circ J. 2011;75(6):1287-96.

125: Indolfi C, Gasparri C, Vicinanza C, De Serio D, Boncompagni D, Mongiardo A, Spaccarotella C, Agosti V, Torella D, Curcio A. Mitogen-activated protein kinases activation in T lymphocytes of patients with acute coronary syndromes. Basic Res Cardiol. 2011 Jun;106(4):667-79. doi: 10.1007/s00395-011-0172-1.

126: Esposito G, Perrino C, Cannavo A, Schiattarella GG, Borgia F, Sannino A, Pironti G, Gargiulo G, Di Serafino L, Franzone A, Scudiero L, Grieco P, Indolfi C, Chiariello M. EGFR trans-activation by urotensin II receptor is mediated by β-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy. Basic Res Cardiol. 2011 Jun;106(4):577-89. doi:10.1007/s00395-011-0163-2.

127: Krishnan S, Gaspari M, Della Corte A, Bianchi P, Crescente M, Cerletti C, Torella D, Indolfi C, de Gaetano G, Donati MB, Rotilio D, Cuda G. OFFgel-based multidimensional LC-MS/MS approach to the cataloguing of the human platelet proteome for an interactomic profile. Electrophoresis. 2011 Mar;32(6-7):686-95. doi: 10.1002/elps.201000592.

128: Gambardella A, Curcio A, Labate A, Mumoli L, Indolfi C, Quattrone A. Blocking out the real diagnosis. Lancet. 2011 Feb 19;377(9766):690. doi:10.1016/S0140-6736(10)61496-1.

129: Santarpia G, Scognamiglio G, Di Salvo G, D’Alto M, Sarubbi B, Romeo E, Indolfi C, Cotrufo M, Calabrò R. Aortic and left ventricular remodeling in patients with bicuspid aortic valve without significant valvular dysfunction: a prospective study. Int J Cardiol. 2012 Jul 26;158(3):347-52. doi: 10.1016/j.ijcard.2011.01.046.

130: Santarpino G, Rubino AS, Onorati F, Curcio A, Torella D, Tucci L, Indolfi C, Renzulli A. Atrial fibrillation ablation induces reverse remodelling and impacts cardiac function. Minerva Cardioangiol. 2011 Feb;59(1):17-29.

131: Spaccarotella C, Mongiardo A, Indolfi C. Pathophysiology of aortic stenosis and approach to treatment with percutaneous valve implantation. Circ J. 2011;75(1):11-19.

132: Bianchi R, Torella D, Spaccarotella C, Mongiardo A, Indolfi C. Mediterranean jellyfish sting-induced Tako-Tsubo cardiomyopathy. Eur Heart J. 2011 Jan;32(1):18. doi: 10.1093/eurheartj/ehq349.

133: Torella M, Torella D, Chiodini P, Franciulli M, Romano G, De Santo L, De Feo M, Amarelli C, Sasso FC, Salvatore T, Ellison GM, Indolfi C, Cotrufo M, Nappi G. LOWERing the INtensity of oral anticoaGulant Therapy in patients with bileaflet mechanical aortic valve replacement: results from the “LOWERING-IT” Trial. Am Heart J. 2010 Jul;160(1):171-8. doi: 10.1016/j.ahj.2010.05.005.

134: Gasparri C, Curcio A, Torella D, Gaspari M, Celi V, Salituri F, Boncompagni D, Torella M, Gulletta E, Cuda G, Indolfi C. Proteomics reveals high levels of vitamin D binding protein in myocardial infarction. Front Biosci (Elite Ed). 2010 Jun 1;2:796-804.

135: Perrino C, Feliciello A, Schiattarella GG, Esposito G, Guerriero R, Zaccaro  L, Del Gatto A, Saviano M, Garbi C, Carangi R, Di Lorenzo E, Donato G, Indolfi C, Avvedimento VE, Chiariello M. AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress. Cardiovasc Res. 2010 Oct 1;88(1):101-10. doi: 10.1093/cvr/cvq155.

136: Mastroroberto P, Onorati F, Zofrea S, Renzulli A, Indolfi C. Outcome of open and endovascular repair in acute type B aortic dissection: a retrospective and observational study. J Cardiothorac Surg. 2010 Apr 9;5:23. doi:10.1186/1749-8090-5-23.

137: Ribichini F, Ansalone G, Bartorelli A, Beqaraj F, Berni A, Colangelo S, D’Amico M, Della Rovere F, Fiscella A, Gabrielli G, Indolfi C, La Vecchia L, Loschiavo P, Marinoni G, Marzocchi A, Milazzo D, Romano M, Sangiorgio P, Sheiban I, Tamburino C, Tuccillo B, Villani R, Cappi B, Quijada MJ, Vassanelli C; EXECUTIVE Trial Investigators. A clinical and angiographic study of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with multivessel coronary artery disease. Study design and rationale of the EXECUTIVE trial. J Cardiovasc Med (Hagerstown). 2010 Apr;11(4):299-309. doi:10.2459/JCM.0b013e3283331e69.

138: Ellison GM, Galuppo V, Vicinanza C, Aquila I, Waring CD, Leone A, Indolfi C, Torella D. Cardiac stem and progenitor cell identification: different markers for the same cell? Front Biosci (Schol Ed). 2010 Jan 1;2:641-52.

139: Elia L, Quintavalle M, Zhang J, Contu R, Cossu L, Latronico MV, Peterson KL, Indolfi C, Catalucci D, Chen J, Courtneidge SA, Condorelli G. The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease. Cell Death Differ. 2009 Dec;16(12):1590-8. doi: 10.1038/cdd.2009.153.

140: Torella D, Gasparri C, Ellison GM, Curcio A, Leone A, Vicinanza C, Galuppo V, Mendicino I, Sacco W, Aquila I, Surace FC, Luposella M, Stillo G, Agosti V, Cosentino C, Avvedimento EV, Indolfi C. Differential regulation of vascular smooth muscle and endothelial cell proliferation in vitro and in vivo by cAMP/PKA-activated p85alphaPI3K. Am J Physiol Heart Circ Physiol. 2009 Dec;297(6):H2015-25. doi: 10.1152/ajpheart.00738.2009.

141: Gentile F, Curcio A, Indolfi C, Ferrari M, Decuzzi P. The margination propensity of spherical particles for vascular targeting in the microcirculation. J Nanobiotechnology. 2008 Aug 15;6:9. doi: 10.1186/1477-3155-6-9.

142: Onorati F, Curcio A, Santarpino G, Torella D, Mastroroberto P, Tucci L, Indolfi C, Renzulli A. Routine ganglionic plexi ablation during Maze procedure improves hospital and early follow-up results of mitral surgery. J Thorac Cardiovasc Surg. 2008 Aug;136(2):408-18. doi: 10.1016/j.jtcvs.2008.03.022.

143: Onorati F, Pasceri E, Scalas C, Santarpino G, Mastroroberto P, Indolfi C, Renzulli A. Aortic tube grafts wrapping with hemostatic fleeces reduces postoperative pericardial effusions. J Cardiovasc Surg (Torino). 2008 Jun;49(3):393-7.

144: Mastroroberto P, di Virgilio A, Renzulli A, Indolfi C. Endovascular repair of type B aortic dissection: is it possible to prevent post-procedure complications? Eur J Cardiothorac Surg. 2008 May;33(5):945-6; author reply 946-7.doi: 10.1016/j.ejcts.2008.01.036.

145: Savonitto S, De Servi S, Petronio AS, Bolognese L, Cavallini C, Greco C, Indolfi C, Visconti LO, Piscione F, Ambrosio G, Galvani M, Marzocchi A, Santilli I, Steffenino G, Maseri A. Early aggressive vs. initially conservative treatment in elderly patients with non-ST-elevation acute coronary syndrome: the Italian Elderly ACS study. J Cardiovasc Med (Hagerstown). 2008 Mar;9(3):217-26. doi:10.2459/JCM.0b013e3282f7c8df.

146: Torella D, Indolfi C, Goldspink DF, Ellison GM. Cardiac stem cell-based myocardial regeneration: towards a translational approach. Cardiovasc Hematol Agents Med Chem. 2008 Jan;6(1):53-9.

147: Decuzzi P, Gentile F, Granaldi A, Curcio A, Causa F, Indolfi C, Netti P, Ferrari M. Flow chamber analysis of size effects in the adhesion of spherical particles. Int J Nanomedicine. 2007;2(4):689-96.

148: Onorati F, Impiombato B, Ferraro A, Comi MC, Spaccarotella C, Indolfi C, Renzulli A. Transbrachial intraaortic balloon pumping in severe peripheral atherosclerosis. Ann Thorac Surg. 2007 Jul;84(1):264-6.

149: Torella D, Curcio A, Gasparri C, Galuppo V, De Serio D, Surace FC, Cavaliere AL, Leone A, Coppola C, Ellison GM, Indolfi C. Fludarabine prevents smooth muscle proliferation in vitro and neointimal hyperplasia in vivo through specific inhibition of STAT-1 activation. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2935-43.

150: Ellison GM, Torella D, Karakikes I, Purushothaman S, Curcio A, Gasparri C, Indolfi C, Cable NT, Goldspink DF, Nadal-Ginard B. Acute beta-adrenergic overload produces myocyte damage through calcium leakage from the ryanodine receptor 2 but spares cardiac stem cells. J Biol Chem. 2007 Apr 13;282(15):11397-409. Epub 2007 Jan 19.

151: Mazzarotto P, Di Renzi P, Paluello GM, Carunchio A, Ricci R, Molisso A, Ceci V, Indolfi C. Comparison between four-slice computed tomography and coronary angiography for the assessment of coronary stents. J Cardiovasc Med (Hagerstown). 2006 May;7(5):328-34.

152: Fuiano G, Mancuso D, Indolfi C, Mongiardo A, Sabbatini M, Conte G, De Nicola L, Minutolo R, Mazza G, Cianfrone P, Andreucci M. Early detection of progressive renal dysfunction in patients with coronary artery disease. Kidney Int. 2005 Dec;68(6):2773-80. PubMed PMID: 16316352.

153: Ortolani P, Ardissino D, Cavallini C, Bramucci E, Indolfi C, Aquilina M, Marzocchi A. Effect of sirolimus-eluting stent in diabetic patients with small coronary arteries (a SES-SMART substudy). Am J Cardiol. 2005 Nov 15;96(10):1393-8.

154: Torella D, Ellison GM, Nadal-Ginard B, Indolfi C. Cardiac stem and progenitor cell biology for regenerative medicine. Trends Cardiovasc Med. 2005 Aug;15(6):229-36.

155: Sasso FC, Torella D, Carbonara O, Ellison GM, Torella M, Scardone M, Marra C, Nasti R, Marfella R, Cozzolino D, Indolfi C, Cotrufo M, Torella R, Salvatore T. Increased vascular endothelial growth factor expression but impaired vascular endothelial growth factor receptor signaling in the myocardium of type 2 diabetic patients with chronic coronary heart disease. J Am Coll Cardiol. 2005 Sep 6;46(5):827-34.

156: Indolfi C, Achille F, Tagliamonte G, Spaccarotella C, Mongiardo A, Ferraro A. Polytetrafluoroethylene stent deployment for a left anterior descending coronary aneurysm complicated by late acute anterior myocardial infarction. Circulation. 2005 Aug 2;112(5):e70-1.

157: Indolfi C, Mongiardo A, Spaccarotella C, Ferraro A, Torella D. The present and future of drug-eluting stents. Ital Heart J. 2005 Jun;6(6):498-506.

158: Indolfi C, Pavia M, Angelillo IF. Drug-eluting stents versus bare metal stents in percutaneous coronary interventions (a meta-analysis). Am J Cardiol. 2005 May 15;95(10):1146-52.

159: Ardissino D, Cavallini C, Bramucci E, Indolfi C, Marzocchi A, Manari A, Angeloni G, Carosio G, Bonizzoni E, Colusso S, Repetto M, Merlini PA; SES-SMART Investigators. Sirolimus-eluting vs uncoated stents for prevention of restenosis in small coronary arteries: a randomized trial. JAMA. 2004 Dec 8;292(22):2727-34.

160: Di Mario C, Bolognese L, Maillard L, Dudek D, Gambarati G, Manari A, Guiducci V, Patrizi G, Rusconi LC, Piovaccari G, Hibon AR, Belpomme V, Indolfi C, Olivari Z, Steffenino G, Zmudka K, Airoldi F, Panzarasa R, Flather M, Steg PG. Combined Abciximab REteplase Stent Study in acute myocardial infarction (CARESS in AMI). Am Heart J. 2004 Sep;148(3):378-85.

161: Mongiardo A, Curcio A, Spaccarotella C, Parise S, Indolfi C. Molecular mechanisms of restenosis after percutaneous peripheral angioplasty and approach to endovascular therapy. Curr Drug Targets Cardiovasc Haematol Disord. 2004 Sep;4(3):275-87.

162: Indolfi C, Berardi F, Bolognese L, Danzi GB, Galassi AR, Della Grazia E, Montinaro A, Paloscia L, Vassanelli C, Bartorelli A, Klugmann S, Petronio AS, Scherillo M, Marzilli M; Società Italiana di Cardiologia Invasiva. [Italian Consensus Conference on drug-eluting stents]. Ital Heart J Suppl. 2004 Jan;5(1):64-70.

163: Torella D, Leosco D, Indolfi C, Curcio A, Coppola C, Ellison GM, Russo VG, Torella M, Li Volti G, Rengo F, Chiariello M. Aging exacerbates negative remodeling and impairs endothelial regeneration after balloon injury. Am J Physiol Heart Circ Physiol. 2004 Dec;287(6):H2850-60.

164: Corbucci GG, Perrino C, Donato G, Ricchi A, Lettieri B, Troncone G, Indolfi C, Chiariello M, Avvedimento EV. Transient and reversible deoxyribonucleic acid damage in human left ventricle under controlled ischemia and reperfusion. J Am Coll Cardiol. 2004 Jun 2;43(11):1992-9.

165: Curcio A, Torella D, Cuda G, Coppola C, Faniello MC, Achille F, Russo VG, Chiariello M, Indolfi C. Effect of stent coating alone on in vitro vascular smooth muscle cell proliferation and apoptosis. Am J Physiol Heart Circ Physiol. 2004 Mar;286(3):H902-8.

166: Indolfi C, Mongiardo A, Curcio A, Torella D. Molecular mechanisms of in-stent restenosis and approach to therapy with eluting stents. Trends Cardiovasc Med. 2003 May;13(4):142-8.

167: Indolfi C, Curcio A, Chiariello M. Simvastatin reduces neointimal thickening after experimental angioplasty. Circulation. 2003 Jan 28;107(3):e25.

168: Indolfi C, Torella D, Rapacciuolo A, Coppola C, Curcio A, Chiariello M. [Molecular therapeutic strategies in cardiology]. Cardiologia. 1999 Dec;44 Suppl  1(Pt 2):1033-6

169: Indolfi C, Stabile E, Esposito G, Perrino C, Cavuto L, Guerrera L, Chiariello M. [New horizons in revascularization: neoangiogenesis]. Cardiologia. 1999 Dec;44 Suppl 1(Pt 2):565-7.

170: Indolfi C, Torella D, Coppola C, Curcio A, Rodriguez F, Bilancio A, Leccia A, Arcucci O, Falco M, Leosco D, Chiariello M. Physical training increases eNOS vascular expression and activity and reduces restenosis after balloon angioplasty or arterial stenting in rats. Circ Res. 2002 Dec 13;91(12):1190-7.

171: Indolfi C, Di Lorenzo E, Perrino C, Stingone AM, Curcio A, Torella D, Cittadini A, Cardone L, Coppola C, Cavuto L, Arcucci O, Sacca L, Avvedimento EV, Chiariello M. Hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin prevents cardiac hypertrophy induced by pressure overload and inhibits p21ras activation. Circulation. 2002 Oct 15;106(16):2118-24.

172: Piscione F, Galasso G, Maione AG, Pisani A, Golino P, Leosco D, Indolfi C, Chiariello M. Immediate and long-term outcome of recanalization of chronic total coronary occlusions. J Interv Cardiol. 2002 Jun;15(3):173-9.

173: Indolfi C, Torella D, Coppola C, Stabile E, Esposito G, Curcio A, Pisani A, Cavuto L, Arcucci O, Cireddu M, Troncone G, Chiariello M. Rat carotid artery dilation by PTCA balloon catheter induces neointima formation in presence of IEL rupture. Am J Physiol Heart Circ Physiol. 2002 Aug;283(2):H760-7.

174: Curcio A, Torella D, Coppola C, Mongiardo A, Cireddu M, Falco M, Chiariello M, Indolfi C. Coated stents: a novel approach to prevent in-stent restenosis. Ital Heart J. 2002 Jun;3 Suppl 4:16S-19S.

175: Mongiardo A, Ferraro A, Ceravolo R, Mascaro G, Curcio A, Campopiano E, Indolfi C. [Mechanism of troponin and CK-MB release after percutaneous coronary interventions]. Ital Heart J Suppl. 2002 Mar;3(3):270-4.

176: Piscione F, Perrone-Filardi P, De Luca G, Prastaro M, Indolfi C, Golino P, Dellegrottaglie S, Chiariello M. Low dose dobutamine echocardiography for predicting functional recovery after coronary revascularisation. Heart. 2001 Dec;86(6):679-86.

177: Capozzolo C, Piscione F, De Luca G, Cioppa A, Mazzarotto P, Leosco D, Golino P, Indolfi C, Chiariello M. Direct coronary stenting: effect on coronary blood flow, immediate and late clinical results. Catheter Cardiovasc Interv. 2001 Aug;53(4):464-73.

178: Indolfi C, Torella D, Cavuto L, Davalli AM, Coppola C, Esposito G, Carriero MV, Rapacciuolo A, Di Lorenzo E, Stabile E, Perrino C, Chieffo A, Pardo F, Chiariello M. Effects of balloon injury on neointimal hyperplasia in streptozotocin-induced diabetes and in hyperinsulinemic nondiabetic pancreatic islet-transplanted rats. Circulation. 2001 Jun 19;103(24):2980-6.

179: Indolfi C, Coppola C, Torella D, Arcucci O, Chiariello M. Gene therapy for restenosis after balloon angioplasty and stenting. Cardiol Rev. 1999 Nov-Dec;7(6):324-31.

180: Indolfi C, Stabile E, Coppola C, Gallo A, Perrino C, Allevato G, Cavuto L, Torella D, Di Lorenzo E, Troncone G, Feliciello A, Avvedimento E, Chiariello M. Membrane-bound protein kinase A inhibits smooth muscle cell proliferation in vitro and in vivo by amplifying cAMP-protein kinase A signals. Circ Res. 2001 Feb 16;88(3):319-24.

181: Indolfi C, Torella D, Belardo L, Chiariello M. Genetically modified animal models to study cardiovascular disorders. Ital Heart J. 2000 Sep;1 Suppl 3:S49-51.

182: Indolfi C, Di Lorenzo E, Rapacciuolo A, Stingone AM, Stabile E, Leccia A, Torella D, Caputo R, Ciardiello F, Tortora G, Chiariello M. 8-chloro-cAMP inhibits smooth muscle cell proliferation in vitro and neointima formation induced by balloon injury in vivo. J Am Coll Cardiol. 2000 Jul;36(1):288-93.

183: Indolfi C, Esposito G, Stabile E, Cavuto L, Pisani A, Coppola C, Torella D, Perrino C, Di Lorenzo E, Curcio A, Palombini L, Chiariello M. A new rat model of small vessel stenting. Basic Res Cardiol. 2000 Jun;95(3):179-85.

184: Heusch G, Baumgart D, Camici P, Chilian W, Gregorini L, Hess O, Indolfi C, Rimoldi O. alpha-adrenergic coronary vasoconstriction and myocardial ischemia in humans. Circulation. 2000 Feb 15;101(6):689-94.

185: Indolfi C, Cioppa A, Stabile E, Di Lorenzo E, Esposito G, Pisani A, Leccia A, Cavuto L, Stingone AM, Chieffo A, Capozzolo C, Chiariello M. Effects of hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin on smooth muscle cell proliferation in vitro and neointimal formation in vivo after vascular injury. J Am Coll Cardiol. 2000 Jan;35(1):214-21.

186: Indolfi C, Stabile E, Perrino C, Chiariello M. Mechanisms of restenosis after angioplasty and approach to therapy (Review). Int J Mol Med. 1998 Aug;2(2):143-148.

187: Indolfi C, Chiariello M. Gene therapy for cardiovascular disorders. Cardiologia. 1998 Apr;43(4):365-73.

188: Indolfi C, Avvedimento EV, Rapacciuolo A, Esposito G, Di Lorenzo E, Leccia A, Pisani A, Chieffo A, Coppola A, Chiariello M. In vivo gene transfer: prevention of neointima formation by inhibition of mitogen-activated protein kinase kinase. Basic Res Cardiol. 1997 Dec;92(6):378-84.

189: Indolfi C, Avvedimento EV, Di Lorenzo E, Esposito G, Rapacciuolo A, Giuliano P, Grieco D, Cavuto L, Stingone AM, Ciullo I, Condorelli G, Chiariello M. Activation of cAMP-PKA signaling in vivo inhibits smooth muscle cell proliferation induced by vascular injury. Nat Med. 1997 Jul;3(7):775-9.

190: Indolfi C, Di Lorenzo E, Chiariello M. Inhibition of factor Xa and neointima formation after vascular injury. Circulation. 1996 Dec 1;94(11):2998-3001.

191: Perrone-Filardi P, Pace L, Prastaro M, Squame F, Betocchi S, Soricelli A, Piscione F, Indolfi C, Crisci T, Salvatore M, Chiariello M. Assessment of myocardial viability in patients with chronic coronary artery disease. Rest-4-hour-24-hour 201Tl tomography versus dobutamine echocardiography. Circulation. 1996 Dec 1;94(11):2712-9.

192: Indolfi C, Piscione F, Perrone-Filardi P, Prastaro M, Di Lorenzo E, Saccà L, Salvatore M, Condorelli M, Chiariello M. Inotropic stimulation by dobutamine increases left ventricular regional function at the expense of metabolism in hibernating myocardium. Am Heart J. 1996 Sep;132(3):542-9.

193: Chiariello M, Indolfi C. Silent myocardial ischemia in patients with diabetes mellitus. Circulation. 1996 Jun 15;93(12):2089-91.

194: Indolfi C, Chiariello M, Avvedimento EV. Selective gene therapy for proliferative disorders: sense and antisense. Nat Med. 1996 Jun;2(6):634-5.

195: Indolfi C, Piscione F, Ceravolo R, Maione A, Focaccio A, Rao MA, Esposito G, Condorelli M, Chiariello M. Limb vasoconstriction after successful angioplasty of the left anterior descending coronary artery. Circulation. 1995 Oct 15;92(8):2109-12.

196: Indolfi C, Esposito G, Di Lorenzo E, Rapacciuolo A, Feliciello A, Porcellini A, Avvedimento VE, Condorelli M, Chiariello M. Smooth muscle cell proliferation is proportional to the degree of balloon injury in a rat model of angioplasty. Circulation. 1995 Sep 1;92(5):1230-5.

197: Ferro G, Duilio C, Spinelli L, Liucci GA, Mazza F, Indolfi C. Relation between diastolic perfusion time and coronary artery stenosis during stress-induced myocardial ischemia. Circulation. 1995 Aug 1;92(3):342-7.

198: Indolfi C, Avvedimento EV, Rapacciuolo A, Di Lorenzo E, Esposito G, Stabile E, Feliciello A, Mele E, Giuliano P, Condorelli G, et al. Inhibition of cellular ras prevents smooth muscle cell proliferation after vascular injury in vivo. Nat Med. 1995 Jun;1(6):541-5.

199: Perrone-Filardi P, Pace L, Prastaro M, Piscione F, Betocchi S, Squame F, Vezzuto P, Soricelli A, Indolfi C, Salvatore M, et al. Dobutamine echocardiography predicts improvement of hypoperfused dysfunctional myocardium after revascularization in patients with coronary artery disease. Circulation. 1995 May 15;91(10):2556-65.

200: Rapacciuolo A, Indolfi C, Di Lorenzo E, Esposito G, Stabile E, Stingone AM, Avvedimento EV, Condorelli M, Chiariello M. [Gene therapy for the treatment of restenosis after coronary angioplasty]. Cardiologia. 1994 Dec;39(12):843-7.

201: Piscione F, Ceravolo R, Indolfi C, Perrone-Filardi P, Prastaro M, Focaccio A, Pace L, Vezzuto P, Chiariello M. [Coronary angioplasty for the recovery of myocardial function after acute myocardial infarction: mid- and long-term results]. Cardiologia. 1994 Dec;39(12 Suppl 1):441-9.

202: Indolfi C, Piscione F, Rapacciuolo A, Esposito G, Esposito N, Ceravolo R, Di Lorenzo E, Maione A, Condorelli M, Chiariello M. Coronary artery vasoconstriction after successful single angioplasty of the left anterior descending artery. Am Heart J. 1994 Nov;128(5):858-64.

203: Indolfi C, Rapacciuolo A, Condorelli M, Chiariello M. Alpha-adrenergic control of coronary circulation in man. Basic Res Cardiol. 1994 Sep-Oct;89(5):381-96.

204: Bonaduce D, Petretta M, Piscione F, Indolfi C, Migaux ML, Bianchi V, Esposito N, Marciano F, Chiariello M. Influence of reversible segmental left ventricular dysfunction on heart period variability in patients with one-vessel coronary artery disease. J Am Coll Cardiol. 1994 Aug;24(2):399-405.

205: Indolfi C, Maione A, Volpe M, Rapacciuolo A, Esposito G, Ceravolo R, Rendina V, Condorelli M, Chiariello M. Forearm vascular responsiveness to alpha 1- and alpha 2-adrenoceptor stimulation in patients with congestive heart failure. Circulation. 1994 Jul;90(1):17-22.

206: Miura T, Miyazaki S, Guth BD, Indolfi C, Ross J Jr. Heart rate and force-frequency effects on diastolic function of the left ventricle in exercising dogs. Circulation. 1994 May;89(5):2361-8.

207: Golino P, Piscione F, Benedict CR, Anderson HV, Cappelli-Bigazzi M, Indolfi C, Condorelli M, Chiariello M, Willerson JT. Local effect of serotonin released during coronary angioplasty. N Engl J Med. 1994 Feb 24;330(8):523-8.

208: Esposito G, Piscione F, Giunta A, Indolfi C, Maione S, Arnese MR, Condorelli M, Chiariello M. [The effects of the selective intracoronary administration of nifedipine on left ventricular filling anomalies during coronary angioplasty].Cardiologia. 1993 Aug;38(8):503-11.

209: Miura T, Bhargava V, Guth BD, Sunnerhagen KS, Miyazaki S, Indolfi C, Peterson KL. Increased afterload intensifies asynchronous wall motion and impairs ventricular relaxation. J Appl Physiol (1985). 1993 Jul;75(1):389-96.

210: Indolfi C, Ross J Jr. The role of heart rate in myocardial ischemia and infarction: implications of myocardial perfusion-contraction matching. Prog Cardiovasc Dis. 1993 Jul-Aug;36(1):61-74. Review.

211: Miyazaki S, Goto Y, Guth BD, Miura T, Indolfi C, Ross J Jr. Changes in regional myocardial function and external work in exercising dogs with ischemia. Am J Physiol. 1993 Jan;264(1 Pt 2):H110-6.

212: Rapacciuolo A, Indolfi C, Esposito G, Di Lorenzo E, Esposito N, Maione A, Ambrosini V, Piscione F, Chiariello M. [Coronary vasoconstriction induced by digoxin in normal subjects and in patients with coronary atherosclerosis]. Cardiologia. 1993 Jan;38(1):19-24.

213: Maione A, Rapacciuolo A, Esposito G, Di Lorenzo E, Ceravolo R, Indolfi C, Chiariello M. [Effect of alpha-adrenergic receptor blockade on peripheral vasoconstriction induced by the cold pressor test. Evidence for functional integrity of alpha 1 and alpha 2 adrenergic receptors in patients with congestive heart failure]. Cardiologia. 1992 Dec;37(12):839-45.

214: Indolfi C, Piscione F, Villari B, Russolillo E, Rendina V, Golino P, Condorelli M, Chiariello M. Role of alpha 2-adrenoceptors in normal and atherosclerotic human coronary circulation. Circulation. 1992 Oct;86(4):1116-24.

215: Indolfi C, Piscione F, Russolillo E, Villari B, Golino P, Ambrosini V, Condorelli M, Chiariello M. Digoxin-induced vasoconstriction of normal and atherosclerotic epicardial coronary arteries. Am J Cardiol. 1991 Nov 15;68(13):1274-8.

216: Indolfi C, Guth BD, Miyazaki S, Miura T, Schulz R, Ross J Jr. Heart rate reduction improves myocardial ischemia in swine: role of interventricular blood flow redistribution. Am J Physiol. 1991 Sep;261(3 Pt 2):H910-7.

217: Indolfi C, Piscione F, Volpe M, Lembo G, De Campora P, Russolillo E, Ambrosini V, Condorelli M, Chiariello M. [The effects of atrial natriuretic peptide on left ventricular function in subjects with heart failure]. Cardiologia. 1991 May;36(5):351-6

218: Golino P, Piscione F, Willerson JT, Cappelli-Bigazzi M, Focaccio A, Villari B, Indolfi C, Russolillo E, Condorelli M, Chiariello M. Divergent effects of serotonin on coronary-artery dimensions and blood flow in patients with coronary atherosclerosis and control patients. N Engl J Med. 1991 Mar 7;324(10):641-8.

219: Indolfi C, Chiariello M. [The physiopathological mechanisms of transient regional myocardial ischemia and the approach to therapy]. Cardiologia. 1991 Feb;36(2):153-63.

220: Volpe M, Lembo G, Condorelli G, De Luca N, Lamenza F, Indolfi C, Trimarco B. Converting enzyme inhibition prevents the effects of atrial natriuretic factor on baroreflex responses in humans. Circulation. 1990 Oct;82(4):1214-21.

221: Miyazaki S, Guth BD, Miura T, Indolfi C, Schulz R, Ross J Jr. Changes of left ventricular diastolic function in exercising dogs without and with ischemia. Circulation. 1990 Mar;81(3):1058-70.

222: Guth BD, Indolfi C, Heusch G, Seitelberger R, Ross J Jr. Mechanisms of benefit in the ischemic myocardium due to heart rate reduction. Basic Res Cardiol. 1990;85 Suppl 1:157-66.

223: Indolfi C, Betocchi S, Piscione F, Perrone-Filardi P, Salvatore M, Chiariello M. Assessment of left ventricular function using radionuclide angiography after dipyridamole infusion. Chest. 1989 Nov;96(5):1026-30.

224: Indolfi C, Guth BD, Miura T, Miyazaki S, Schulz R, Ross J Jr. Mechanisms of improved ischemic regional dysfunction by bradycardia. Studies on UL-FS 49 in swine. Circulation. 1989 Oct;80(4):983-93.

225: Indolfi C, Piscione F, Volpe M, Focaccio A, Trimarco B, Condorelli M, Chiariello M. [Effects of atrial natriuretic peptide on left ventricular function in man]. Cardiologia. 1989 Mar;34(3):253-7.

226: Indolfi C, Piscione F, Volpe M, Focaccio A, Lembo G, Trimarco B, Condorelli M, Chiariello M. Cardiac effects of atrial natriuretic peptide in subjects with normal left ventricular function. Am J Cardiol. 1989 Feb 1;63(5):353-7.

227: Perrone-Filardi P, Betocchi S, Giustino G, Piscione F, Indolfi C, Salvatore M, Chiariello M. Influence of left ventricular asynchrony on filling in coronary artery disease. Am J Cardiol. 1988 Sep 15;62(9):523-7.

228: Volpe M, De Luca N, Indolfi C, Mele AF, Rivera MP, Condorelli M, Trimarco B. Acute hemodynamic effects of atrial natriuretic peptide in essential hypertension. Kidney Int Suppl. 1988 Sep;25:S83-5.

229: Piscione F, Villari B, Focaccio A, Cappelli-Bigazzi M, Indolfi C. [Percutaneous brachial approach in left cardiac catheterization]. G Ital Cardiol. 1988 Aug;18(8):719-22.

230: Volpe M, DeLuca N, Atlas SA, Camargo MJ, Indolfi C, Lembo G, Trimarco B, Condorelli M, Laragh JH. Reduction of atrial natriuretic factor circulating levels by endogenous sympathetic activation in hypertensive patients. Circulation. 1988 May;77(5):997-1002.

231: Piscione F, Villari B, Focaccio A, Cappelli-Bigazzi M, Indolfi C, Chiariello M. [Percutaneous brachial approach in left heart catheterization with 5 French catheters. Preliminary experience]. G Ital Cardiol. 1988 Jan;18(1):17-22.

232: Volpe M, Mele AF, Indolfi C, De Luca N, Lembo G, Focaccio A, Condorelli M, Trimarco B. Hemodynamic and hormonal effects of atrial natriuretic factor in patients with essential hypertension. J Am Coll Cardiol. 1987 Oct;10(4):787-93.

233: Romano M, Carella G, Cotecchia MR, Di Maro T, Indolfi C, Ferro G, Chiariello M. Abnormal systolic time intervals in obesity and their relationship with the amount of overweight. Am Heart J. 1986 Aug;112(2):356-60.

234: Chiariello M, Indolfi C, Cotecchia MR, Sifola C, Romano M, Condorelli M. Asymptomatic transient ST changes during ambulatory ECG monitoring in diabetic patients. Am Heart J. 1985 Sep;110(3):529-34.

235: Piscione F, Indolfi C, Cotecchia MR, Ascoli R, Chiariello M. [Myocardial infarction in a patient with multiple coronary aneurysms]. Cardiologia. 1984 Nov;29(11):585-90.

236: Romano M, Chiariello M, Ascoli R, Sotgiu P, Guerra G, Carella G, Indolfi C, Ferro G. [Variations in the duration of electromechanical systole and R wavevoltage in normal subjects during dynamic exercise]. Minerva Cardioangiol. 1984 Jul-Aug;32(7-8):529-33.

237: Chiariello M, Indolfi C, Condorelli M. Congenital absence of the pericardium associated with atrial septal defect and sick sinus syndrome. Int J Cardiol. 1984 Apr;5(4):527-30.

238: Piscione F, Betocchi S, Caruso A, Golino P, Indolfi C, Chiariello M. [Severe mitral insufficiency without left atrial hypertension]. Cardiologia. 1984 Mar-Apr;29(3-4):173-9.

239: Chiariello M, Indolfi C, Cappelli Bigazzi M, Condorelli M. Prajmalium bitartrate in chronic ventricular arrhythmias: comparison with disopyramide. Eur J Clin Pharmacol. 1983;24(1):35-9.

Lettera di referenza da parte del Prof John Ross, Universita della california, per la promozione a prof. associato del prof Indolfi. anno 1991

Catanzaro, 16 Gennaio 2019

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Prof. Ciro Indolfi Presidente SIC